Busulfan injection msds
WebBusulfan is a small, highly lipophilic molecule that crosses the blood-brain-barrier. The absolute bioavailability, if a single 2 mg IV bolus injection is given to adult patients, is 80% ± 20%. In children (1.5 - 6 years old), the absolute bioavailability was 68% ± 31%. WebCommercially available busulfan for injection concentrate should be stored in unopened ampules at 2-8 °C. The manufacturer states that, when diluted as directed in 0.9% sodium chloride injection or 5% dextrose injection, …
Busulfan injection msds
Did you know?
Web®(busulfan)Injection Synonyms Busulfan injectable Identified uses Drug products Supplier’s details Otsuka Pharmaceutical Co., Ltd. 2-9 Kanda-Tsukasamachi, Chiyoda-ku Tokyo 101-8535, Japan (Also see section 16) Emergency telephone number Telephone: +81-88-672-6080 (Monday–Friday, 8:00–17:00, JPT) Telefax: +81-88-637-5520 WebBusulfan Injection, 6 mg/ml Manufacturer Agila Specialities Pvt. Ltd. a Mylan Company Product code Revision date 2014 October 30 Language English
WebJun 18, 2014 · Busulfan Concentrate Injection Description. Busulfan is a bifunctional alkylating agent known chemically as 1,4-butanediol, dimethanesulfonate. Busulfan injection is intended for intravenous … WebJun 18, 2014 · Administer Busulfan Injection in combination with cyclophosphamide as a conditioning regimen prior to bone marrow or peripheral blood progenitor cell replacement. For patients weighing more …
WebJun 18, 2014 · The intravenous administration of busulfan (48 mg/kg given as biweekly doses of 12 mg/kg, or 30% of the total Busulfan Injection dose on a mg/m 2 basis) has been shown to increase the incidence of thymic and ovarian tumors in mice. Busulfan depleted oocytes of female rats and induced sterility in male rats and hamsters. WebNDA 20-954 Busulfex (busulfan) Injection h:\20954lbl.doc 02/10/99 P age 2 of 28 BUSULFEX is intended for dilution with 0.9% Sodium Chloride Injection, USP or 5% …
WebBusulfan injection is used to treat a certain type of chronic myelogenous leukemia (CML; a type of cancer of the white blood cells) in combination with other medications to destroy bone marrow and cancer cells in preparation for a bone marrow transplant. Busulfan is in a class of medications called alkylating agents.
WebMay 18, 2024 · Administer Busulfan Injection in combination with cyclophosphamide as a conditioning regimen prior to bone marrow or peripheral blood progenitor cell replacement. For patients weighing more than 12 kg, the recommended doses are: team practice packagesso you go like thisWebJun 18, 2014 · Busulfan Injection is a cytotoxic drug. Follow applicable special handling and disposal procedures. Skin reactions may occur with accidental exposure. Use gloves … team ppt template freeWebJun 18, 2014 · Busulfan Injection dosing was targeted to achieve an area under the plasma concentration curve (AUC) of 900–1350 µM∙min with an initial dose of 0.8 mg per kg or 1.0 mg per kg (based on Actual Body Weight (ABW)) if the patient was greater than 4 or less than or equal to 4 years, respectively. The dose was adjusted based on plasma ... team ppt templateWebJun 18, 2014 · Busulfan Injection dosing was targeted to achieve an area under the plasma concentration curve (AUC) of 900–1350 µM∙min with an initial dose of 0.8 mg per kg or 1.0 mg per kg (based on Actual Body Weight (ABW)) if the patient was greater than 4 or less than or equal to 4 years, respectively. so you girls remember thatWebFeb 17, 2024 · Busulfan injection contains N,N-dimethylacetamide, which may be incompatible with some closed-system transfer devices (CSTDs); the plastic components of some CSTDs may dissolve and result in subsequent leakage and potential infusion of dissolved plastic into the patient (ISMP [Smetzer 2015]). Refer to the specific CSTD … so you can sharpen your knifeWebJun 18, 2014 · Busulfan Injection dosing was targeted to achieve an area under the plasma concentration curve (AUC) of 900–1350 µM∙min with an initial dose of 0.8 mg per kg or 1.0 mg per kg (based on Actual Body Weight (ABW)) if the patient was greater than 4 or less than or equal to 4 years, respectively. The dose was adjusted based on plasma ... so you found a tarantula