Klf2 hematopoietic stem cell
Webcultured endothelial cells, where it regulates a large number of vasoactive endothelial genes. Here, we show that Klf2 expression during development mirrors the rise of fluid shear … WebJun 5, 2014 · Klf2 is an essential factor that sustains ground state pluripotency Authors Jia-Chi Yeo 1 , Jianming Jiang 2 , Zi-Ying Tan 3 , Guo-Rong Yim 2 , Jia-Hui Ng 2 , Jonathan Göke 2 , Petra Kraus 4 , Hongqing Liang 2 , Kevin Andrew Uy Gonzales 5 , Han-Chung Chong 6 , Cheng-Peow Tan 2 , Yee-Siang Lim 2 , Nguan-Soon Tan 7 , Thomas Lufkin 4 , Huck-Hui Ng 8
Klf2 hematopoietic stem cell
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WebKLF2 has been most widely studied for its role in hematopoietic cell biology and inflammatory diseases shown in Figure1. It is also known as lung Kruppel-like factor (LKLF) based on its first ... KLF2 in T Cells KLF2 is expressed in single-positive CD4+ and CD8+ T cells and remains highly expressed in both naïve and memory T cells [5]. Its ... WebNational Center for Biotechnology Information
WebThe Krüppel-like factor (Klf) family are key transcription factors implicated in self-renewal of embryonic stem cells. Here we identify Klf2 as a crucial transcription factor in … WebNov 13, 2024 · Krüppel-like Factor 2 (KLF2) is an important indicator of the stemness of human MSCs (hMSCs) and as early vascularization is also critical for bone regeneration, we used KLF2 as a novel in vitro marker for MSCs and investigated the angiogenesis and osteogenesis between KLF2 + MSCs and endothelial cells (ECs).
WebMay 10, 2016 · In terms of NK cell expansion and survival, we now report that Kruppel-like factor 2 (KLF2) is a key transcription factor that underpins both of these events. Excision … WebMar 21, 2024 · KLF2 (KLF Transcription Factor 2) is a Protein Coding gene. Diseases associated with KLF2 include Cerebral Cavernous Malformations and Spleen Cancer. …
Webof KLF2 was observed in myeloid cells and no substantial effect was seen on other major hematopoietic lineages, tissues, or monocytic subsets (Figure S1 available online). Previous work from our lab and others implicated KLF2 as a critical transcrip-tion factor that maintains cellular quiescence (Bista et al.,
WebOct 13, 2011 · Fourth, Klf2a directly regulates nos1 and nos2, and thereby promotes the role of NO signaling in HSC development. These data lead us to propose a model in which … rhea agojoWebThesis: The roles of transcription factors Krüppel Like factor1 (KLF1) and KLF2 in human globin gene regulation and fetal erythropoiesis. • … rhd ukWebJul 9, 2009 · Studies done with KLF2 deficiency limited to only hematopoietic cells reported a striking loss of T cells from the blood, lymph node, and spleen and grossly normal thymic development ( Kuo et al., 1997b ). Our laboratory previously reported an increase of mature CD4 and CD8 single positive (SP) cells in the KLF2-deficient thymus ( rheadawn davis live kokomo indianaWebAug 30, 2007 · KLF2, or LKLF (lung Kruppel-like factor), is highly expressed in T cells, and targeted disruption of KLF2 verified an essential role for this factor in programming and maintaining naïve T-cell quiescence ( Kuo et al, 1997 ). rhea bijuWebApr 14, 2024 · The BK virus (BKV) causes severe hemorrhagic cystitis in hematopoietic stem cell transplant (HSCT) recipients. To eliminate reactivated BKV, symptomatic patients can be treated with a reduction of the immunosuppressive therapy, with the antiviral drug cidofovir, or with virus-specific T cells (VSTs). In the current study, we compared the … rhea godinWebHiroshi Kato, Andras Perl, in Molecules to Medicine with mTOR, 2016. 17.9 Roles of mTOR in CD8 + T-Cell Development. Similar to CD4 + T cells, quiescence of naïve CD8 + T cells is … rhea d.o.o. buzinski prilazWebMar 28, 2024 · Krüppel-like factor 2 (KLF2) is a potent regulator of lymphocyte differentiation, activation and migration. However, its functional role in adaptive and humoral immunity remains elusive. rhdv2 map 2021 uk