Line1 orf1 antibody
Nettet结果: 制备的line1-orf1p抗体效价 > 1:16 000,能对细胞及肿瘤组织内line1-orf1p特异识别。转染pegfp-n1-line1-orf1的wt_cls1细胞,其line1-orf1的mrna及蛋白水平显著增高(p … Nettetwww.ncbi.nlm.nih.gov
Line1 orf1 antibody
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NettetAn active LINE-1 encodes for 2 proteins translated from a single RNA containing two non-overlapping ORFs, ORF1 and ORF2. ORF2p is described in this entry as a representative of all ORF2p potentially expressed by active elements. ORF1p is described in the related entry AC Q9UN81. Nettet9. jun. 2013 · In total, 12 antibodies were tested; α-PCBP2 (Abnova), α-FBL (Santa Cruz) and α-TOP1 (Spring) failed to detect their endogenous targets in pc-L1-1FH …
NettetActivation of L1 expression in human cancers has been detected with an ORF1 antibody 4. ... Van Meter M et al. SIRT6 represses LINE1 retrotransposons by ribosylating KAP1 but this repression fails with stress and age. Nat Commun 5, 5011 (2014). [PMC free article] [Google Scholar] 8. NettetBy evaluating the expression of LINE1 elements, it was found that high levels of ORF1 occur more frequently in breast and ovarian cancer (Chen et al., 2012; Rodic et al., …
NettetLINE-1 ORF1p antibody validated for IHC-P from a verified customer review. Reviewed Applications. Read 1 Review rated 1 using. NBP2-66934 in the following applications: … Nettet10. okt. 2024 · a In situ hybridization of LINE1 Orf1 mRNA in adult WT and Pnldc1 Mut (Mut-1) testes. LINE1 Orf1 mRNA was upregulated in spermatocytes in Pnldc1 Mut …
NettetAnti-LINE-1 ORF1p Antibody, clone 4H1 Detect LINE-1 retrotransposable element ORF1 protein using this mouse monoclonal Anti-LINE-1 ORF1p Anibody, clone 4H1, Cat. No. MABC1152. It is used in Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, and Western Blotting. - Find MSDS or SDS, a COA, data sheets …
hand held electric trimmerNettet9. jun. 2013 · LINE-1 (L1) is a non-LTR intragenomic DNA parasite that has been evolving in mammalian genomes for ∼100 Myr. It is the only autonomously active mobile genetic element in humans and constitutes ∼20%... hand held electric whisk argosNettet26. feb. 2024 · For a line carrying a single autosomal recessive mutation of interest, roughly one half of G2 females were expected to be carriers and one eighth of all G3 males were expected to be homozygous. (B) Screen results obtained for the yama line where the F1 male was harem-bred to seven G2 females. bushel wheat per acreNettetL1 encodes two proteins designated as ORF1p and ORF2p and expression of both proteins are critical for the process of retrotransposition. Here we have analyzed L1 … handheld electric welding machineNettetBackground The L1 (LINE-1), or Long INterspersed Element , retrotransposon ORF2 is the most common open reading frame in the human genome, present in various forms in many thousands of copies. This large family of proteins includes magnesium dependent endonucleases and a large number of phosphatases involved in intracellular signaling. hand held electric wire brushNettet31. des. 2024 · To test whether ORF2p could be detected with specific reagents, we developed and validated five rabbit monoclonal antibodies with immunoreactivity for … bushel weights and measuresNettet10. feb. 1995 · Previous studies suggested that multiple forms of ORF1 protein are expressed in mouse cells of different types(6, 7, 10).In extracts from F9 cells that have been metabolically labeled with [35 S]methionine, two polypeptides that immunoprecipitate with ORF1 antibody are detected (Fig. 2 A, lane2, arrows).The largest of these two can … bushel wheat weight